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pbserum Smartker® –  innovative cosmetic line featuring recombinant Keratinase

​pbserum Smartker® is a cosmetic line developed to improve skin texture and overall appearance through targeted enzymatic action. It is based on recombinant keratinase PB333 and designed to support visible skin renewal in a controlled and adaptable way. 

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pbserum Smartker® combines professional treatments and DAILY home care, adapted to such needs as uneven tone, loss of firmness, dehydration, oily or blemish-prone skin, and early signs of ageing.  This integrated approach supports visible results while respecting the skin’s natural balance and physiology.

Keratinase PB333

It is an intelligent enzyme developed using advanced biotechnology by Proteos Biotech. It acts selectively on the outermost skin cells, promoting gentle and natural renewal that enhances the absorption of active ingredients and reveals smoother, brighter, and more even skin from the first applications.

  • It promotes respectful cell renewal without harming the skin.

  • It improves the effectiveness of the active ingredients, helping them to penetrate better.

  • Increases asset retention for a prolonged effect.

  • It enhances the skin's radiance, hydration, and texture.

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Renewal Vit RADIANT Complex Professional

  • Enzyme: Keratinase PB333

  • Composition: Keratinase PB333 + brightening actives

  • Indications: Uneven skin tone, lack of radiance, pigmentation

  • Application: Topical

  • Protocol: 5 sessions, weekly

  • Packaging: 5 units powder + reconstitution solution (5 × 3 mL) + 2 applicators

  • Pairing: DAILY Radiant

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Renewal MULTIVIT Complex Professional

  • Enzyme: Keratinase PB333 + Lipase PB500

  • Composition: Keratinase PB333 + Lipase PB500 + vitamin complex

  • Indications: Dull skin, chronoaging, lack of vitality

  • Application: Topical

  • Protocol: 5 sessions, weekly

  • Packaging: 5 units powder + reconstitution solution (5 × 3 mL) + 2 applicators

  • Pairing: DAILY Oily Skin

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Wrinkle HYALURONIC Complex Professional

  • Enzyme: Keratinase PB333

  • Composition: Keratinase PB333 + hyaluronic acid complex

  • Indications: Dehydrated skin, moisture deficit, early wrinkles

  • Application: Topical

  • Protocol: 5 sessions, weekly

  • Packaging: 5 units powder + reconstitution solution (5 × 3 mL) + 2 applicators

  • Pairing: DAILY Anti-Wrinkle

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Extreme FIRMNESS Complex Professional

  • Enzyme: Keratinase PB333 + Collagenase GH PB220

  • Composition: Keratinase PB333 + Collagenase GH PB220 + firming actives

  • Indications: Loss of firmness, reduced elasticity, skin laxity

  • Application: Topical

  • Protocol: 5 sessions, weekly

  • Packaging: 5 units powder + reconstitution solution (5 × 3 mL) + 2 applicators

  • Pairing: DAILY Firmness

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Renewal Vit EQUILIBRIUM Complex Professional

  • Enzyme: Keratinase PB333

  • Composition: Keratinase PB333 + balancing actives

  • Indications: Oily skin, excess sebum, skin imbalance

  • Application: Topical

  • Protocol: 5 sessions, weekly

  • Packaging: 5 units powder + reconstitution solution (5 × 3 mL) + 2 applicators

  • Pairing: DAILY Anti-Blemish

For Professional Use Only

pbserum Smartker® products are classified as cosmetic formulations and are intended exclusively for aesthetic medicine professionals.

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They are manufactured under strict European quality standards, ensuring safety, consistency, and high formulation quality, including:

• GMP & GLP European manufacturing standards
• Compliance with cosmetic regulatory requirements
• Continuous scientific support and product monitoring ​

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