Pb Serum
BY AUTHORIZED DISTRIBUTOR IN THE BALTICS
About Pbserum
Proteos Biotech (Pbserum) is a Spanish biotechnology laboratory dedicated to advancing aesthetic medicine through recombinant enzyme technology and the development of high-performance, professional-grade skin quality solutions.
Biotechnology Foundation
Developed and manufactured in Spain under GMP and GLP European standards, pbserum integrates advanced recombinant DNA technology to produce highly purified, stable, and efficient enzymes designed for aesthetic applications.
Recombinant Enzyme Expertise
Pbserum is the only biotechnology company globally offering a portfolio of 6 recombinant enzymes for aesthetic bioremodeling, each engineered for precision, selectivity, and controlled action within the skin. These enzymes act as targeted biological tools, enabling personalised protocols that adapt to different skin conditions and treatment goals.
Safety and Quality Standards
All PBserum products are developed under strict European regulatory frameworks, including CE certification and ISO manufacturing standards, ensuring high safety, biocompatibility, and predictable performance in clinical use.
Treatment Philosophy
pbserum solutions are designed to work in harmony with the skin, supporting natural biological processes and delivering visible yet authentic results.
Bioremodeling Innovation
pbserum has introduced enzymatic tissue bioremodeling as a new category in aesthetic medicine — a physiological approach that:
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reorganises tissue structure,
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supports regeneration,
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and improves skin quality without aggressive stimulation.
This strategy focuses on restoring communication within the skin by acting on the extracellular matrix, cellular environment, and structural integrity.
Scientific Evidence and Clinical Approach
The brand is supported by clinical studies, scientific publications, and standardized protocols, ensuring consistent, reproducible outcomes across multiple indications.
6 Recombynant Enzymes
Developed through advanced biotechnological research and engineered using recombinant DNA technology
Keratinase PB333
It is a transepidermal dual delivery system that promotes cell renewal and increases permeability, while respecting the barrier effect of the skin, boosting the retention of active ingredients up to 9 times.
Hyaluronidase PB3000
Catalyses the breakdown of hyaluronic acid, reducing viscosity and improving the permeability of the extracellular matrix. As a result, it enhances microcirculation, promotes lymphatic drainage, and helps achieve a slimmer figure.
Collagenase G & H PB220
2 types of collagenase break down aged collagen fibres and stimulate the production of new fibres by fibroblasts. This reduces the density of fibrotic tissue, improving flexibility and the overall structure of the treated area.
Lipase PB500
It promotes balanced lipid metabolism in the skin, helping to improve its appearance and keep it in good condition. On a superficial level, it contributes to cleaner, more even skin with improved texture.
Lyase PB72K
It acts on proteoglycans, promoting extracellular matrix fluidity, which helps improve skin appearance and provides a feeling of lightness.
Mimicking human enzymes
Unique two-generation technology for using recombinant DNA to create bacterial-origin enzymes that mimic human enzymes.
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Efficacy and Safety
High substrate specificity and selectivity ensure effective treatment for various skin concerns while supporting tissue regeneration and improving skin appearance.
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Purity and Stability
Achieved through freeze-drying (lyophilisation), preserving 100% enzyme activity and ensuring stability without preservatives or additives.
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Low Immunogenicity
Recombinant technology ensures low immunogenicity, supporting safe treatments with minimal risk of adverse immune responses.
Personalised Protocols for Face and Body
Discover PbSerum product lines containing different recombinant enzymes for various skin quality purposes
PbSerum SMARTKER
Non-injectable enzymatic skin quality treatment line designed to improve skin texture, radiance, balance, and overall appearance. It is based on recombinant enzyme keratinase PB333 and supports targeted skin renewal for smoother, clearer, and healthier-looking skin. Indicated for uneven skin tone, lack of radiance, loss of firmness, excess sebum, fine lines, and blemish-prone skin, SMARTKER PROFESSIONAL combines in-office protocols with SMARTKER DAILY home care for consistent, visible results across different skin types.
PbSerum Specific
Non-injectable enzymatic skin quality treatment line designed for targeted skin correction and overall improvement of skin appearance. It is based on a combination of recombinant enzymes, including collagenases, lyase, and keratinase PB333, supporting controlled skin renewal and tissue reorganisation for smoother, more even-looking skin. Indicated for skin ageing, periocular concerns, acne scars, striae, and skin irregularities, PBSERUM SPECIFIC combines in-office protocols with dedicated home care to ensure consistent, visible results across different treatment areas.
PbSerum REVEAL
Enzymatic skin quality treatment line designed to improve skin texture, contour, and overall appearance of face and body. It is based on recombinant enzymes, including collagenases G&H, lyase, and lipase, supporting targeted action on skin irregularities and contour unevenness. Indicated for the submental area, body contour irregularities, skin depressions, visible marks, and uneven skin texture, PBSERUM REVEAL is used in structured in-office protocols for controlled and visible results across different areas.
PbSerum HYAL
Skin quality treatment line designed to improve uneven skin texture and overall appearance. It is based on hyaluronidase PB3000 in different concentrations, supporting targeted action on visible skin irregularities and lack of uniformity.
