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FILLMED ART FILLER® – Haute Sculpture & Regeneration

FILLMED ART FILLER® is a new generation of hyaluronic acid dermal fillers formulated with Tri-Hyal® Technology, designed to deliver tissue induction together with mechanical correction.

 

This comprehensive portfolio of five injectable products — Fine Lines, Universal, Lips Soft, Lips, and Volume — is developed to support skin regeneration by addressing key age-related changes such as wrinkle formation, loss of skin density, volume depletion, and facial contour alterations, while targeting cellular mechanisms in the dermis and hypodermis.

Its regenerative action follows a dual pathway: fibroblast stimulation in the dermis, which supports collagen and elastin synthesis for improved skin density, and adipocyte induction in the hypodermis, which promotes lipid storage and contributes to the restoration of lost facial volume.

The range has been clinically validated in more than 12 publications and supported by over 7 years of clinical experience since its launch in 2016, demonstrating proven safety and efficacy for up to 18 months across multiple facial indications.

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Regenerative Approach

Regeneration refers to the process of replacing or restoring damaged or missing cells, tissues, and organs.


ART FILLER® works on two complementary levels:

  • Mechanical action: restoring lost volume, redefining facial contours, and filling wrinkles.

  • Tissue induction: stimulating fibroblasts and adipocytes to support collagen and elastin synthesis and promote lipid storage, resulting in improved skin density and structure.

This dual mechanism allows ART FILLER® to support regeneration at multiple levels — including dermis redensification and hypodermal volume restoration.

Tri-Hyal® Technology

At the core of ART FILLER® is a unique combination of 3 types of hyaluronic acid:

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Very long chains (>3.7 MDa)

provide structure, cohesivity, and high sculpting potential.

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Long chains (>1.5 MDa)

deliver volume and elasticity.

 

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Free HA (>1.5 MDa)

homogeneously incorporated after cross-linking for sustained biological stimulation and smooth tissue integration.

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Key Advantages

Unique formulation achieves a balance between sculpting, volumising, and smoothing effects while maintaining predictable results, good tissue integration, and a low swelling rate.

  • Proven 18-month efficacy and safety across indications.

  • 1:1 correction predictability with minimal swelling.

  • Strong tissue integration and cohesive structure with no migration.

  • Biological stimulation: activation of fibroblasts (collagen, elastin, HA synthesis) and adipocytes (lipid accumulation, reduced lipolysis).

  • Optimized safety: low residual BDDE and favourable MoD (degree of modification) values.

  • Ergonomic Smart Touch syringe with eco-designed materials for precision and sustainability.

Longest hyaluronic acid chains on the market
(over 3.7 MDa)

Very long and long HA chains form a 3D natural entanglement within the gel, enhancing its moldability, cohesivity, and structural stability once injected. This structure allows the filler to be easily positioned and sculpted, adapting seamlessly to the natural anatomy of the treated area.

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1

Sculpting Potential

Easy-to-shape: the capacity of the gel to be sculpted and positioned accurately within the tissue. This property allows precise contour definition and adaptation to facial anatomy.

2

Volumizing Potential

Elasticity: the capacity of the gel to resist mechanical stress. This ensures structural support and helps restore lost facial volume with long-lasting results.

3

Smoothing Potential

Viscosity: the capacity of the gel to integrate smoothly into the tissue. This promotes natural-looking correction and seamless blending with surrounding structures.

Smart Touch Syringes

Each FILLMED ART FILLER® product is supplied in an advanced Smart Touch syringe — a next-generation delivery system designed to optimise precision, comfort, and safety during injection procedures.

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Next-Generation Syringes

Ergonomic Design for Greater Control

The bi-material structure of the Smart Touch syringe ensures a non-slip grip, allowing practitioners to maintain maximum stability and control throughout the injection process. This ergonomic design supports more precise product placement and contributes to consistently predictable aesthetic results.

Enhanced Injection Safety

The syringe design facilitates safer retroaspiration, enabling practitioners to stabilise their fingers and perform procedures with improved confidence and control. This added safety feature is especially important in sensitive or anatomically complex areas.

Eco-Designed and Sustainable

FILLMED’s Smart Touch syringes are produced with sustainability in mind. They are manufactured from bi-material components, including approximately 30% recycled plastic and 48% bio-sourced materials derived from renewable oils. This reduces plastic use and lowers the carbon footprint by more than 25%.

A Smart Range for Haute Sculpture Corrections

FILLMED ART FILLER® is built as a smart and logical range of 5 hyaluronic acid dermal fillers, each with specifically adapted rheological properties to match the requirements of different facial areas and ageing concerns. This structured approach enables practitioners to perform Haute Sculpture corrections — precise, natural-looking results tailored to each patient’s anatomical needs.

The range provides targeted solutions for:

  • Smoothing superficial wrinkles with soft, low G’ formulations

  • Filling moderate to deep lines and restoring contours with balanced elasticity

  • Enhancing lip volume and definition with medium-to-high G’ gels

  • Restoring facial structure and volume with highly cohesive, high G’ products

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ART FILLER® Volume

  • HA concentration: 25 mg/mL

  • Composition: Very long, long, and free hyaluronic acid (Tri-Hyal® Technology) + 0.3% lidocaine

  • Indications: Volume restoration, contour definition (cheekbones, jawline, chin, temples)

  • Injection depth: Deep dermis to subcutaneous layer

  • Packaging: 2 × 1.2 mL

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ART FILLER® Fine Lines

  • HA concentration: 20 mg/mL

  • Composition: Very long, long, and free hyaluronic acid (Tri-Hyal® Technology) + 0.3% lidocaine

  • Indications: Fine and superficial wrinkles (forehead, crow’s feet, perioral lines, cheek lines)

  • Injection depth: Superficial dermis

  • Packaging: 2 × 1 mL

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ART FILLER® Universal

  • HA concentration: 25 mg/mL

  • Composition: Very long, long, and free hyaluronic acid (Tri-Hyal® Technology) + 0.3% lidocaine

  • Indications: Medium to deep wrinkles (nasolabial folds, marionette lines), lips; off-label: nose

  • Injection depth: Medium to deep dermis

  • Packaging: 2 × 1.2 mL

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ART FILLER® Lips

  • HA concentration: 25 mg/mL

  • Composition: Very long, long, and free hyaluronic acid (Tri-Hyal® Technology) + 0.3% lidocaine

  • Indications: Lip volumization, contour enhancement, deep perioral wrinkles

  • Injection depth: Mid to deep dermis / mucosa

  • Packaging: 1 × 1 mL

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ART FILLER® Lips Soft

  • HA concentration: 25 mg/mL

  • Composition: Very long, long, and free hyaluronic acid (Tri-Hyal® Technology) + 0.3% lidocaine

  • Indications: Soft volume enhancement, moderate perioral wrinkles

  • Injection depth: Superficial to mid-dermis / mucosa (perioral and lip area)

  • Packaging: 1 × 1 mL

FILLMED Signature Protocols

The FILLMED Signature Protocols are advanced injectable treatment strategies that combine the mechanical precision of ART FILLER® with targeted regenerative stimulation to deliver natural, long-lasting aesthetic outcomes. Each protocol is designed to address specific clinical indications and optimise results without surgical intervention.

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3 POINTS ANTI-SAGGING 

FILLMED signature protocol is a non-surgical full-face lifting approach using two types of dermal fillers — ART FILLER® VOLUME and ART FILLER® LIPS — injected into three strategically selected anatomical points.


This targeted technique achieves effective yet natural lifting results, making it ideal for patients with visible skin sagging who wish to avoid surgical procedures.

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DOMINO EFFECT

FILLMED signature protocol is a non-surgical lifting technique performed with ART FILLER® VOLUME dermal filler, injected while avoiding the central part of the face to achieve a very natural lifting effect.

 

The results can last for up to 18 months.

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BIONUTRILIFT

FILLMED Signature Protocol BIONUTRILIFT is an injectable lifting and regenerating treatment that combines the ART FILLER® UNIVERSAL dermal filler with the mesotherapy (regeneration) solution NCTF® 135 HA.

 

The effectiveness of this combination has been demonstrated in clinical studies.

For Professional Use Only

CE-Certified FillMED Art Filler® products are classified as medical devices and intended exclusively for aesthetic medicine professionals.

 

They are manufactured in a dedicated production facility operating under strict international standards, including:

  • ISO 13485 – Quality management system for medical devices

  • ISO 14644 – Cleanroom and controlled environment standards

  • MDSAP certification – Medical Device Single Audit Program (Canada, Australia, Brazil)

 

This ensures consistently high product quality, safety, and compliance with international regulatory requirements.

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