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PROTOCOL: redermalization for periorbital dark circles

The treatment course for skin quality improvement with XELA REDERM can visibly improve dark circles and in this way rejuvenate the overall appearance of the face.

Eye protocol with XELA REDERM 1.1%
  • Product: XELA REDERM 1.1%, amount of product 1-2 ml.

  • Technique: intradermal injections with the papular technique. The diameter of the papula = 1-2 mm, and the distance between the papules is 2-3 mm.

  • Course: 3 procedures with the interval of 2 weeks

Results may vary. Unretouched photos were taken before and after the course of the procedures.

What causes dark circles?

Periorbital dark circles are defined as bilateral, round, homogeneous dark macules on the infraorbital regions. They are usually caused by pathological vascularization, dermal hyperpigmentation, and/or special anatomy.

Redermalization effect on dark circles

Redermalization with a formula containing hyaluronic acid and succinic acid has proven improvement of skin quality by increasing its regenerative potential. Patented renormalization with XELA REDERM can improve periorbital black circles of any indication.

PATHOLOGICAL VASCULARIZATION can be static, with excessive or superficial subcutaneous vasculature (A) or atonic, periorbital edema (B).
Succinic acid to accelerate new vessels growth

The microvascular spasm causes hypoxia that results in a lack of oxygen, water, and nutrients. Consequentially, wrinkles, and dry, thin skin develop.

Weak microcirculation within vessels means that blood enters the tissue, but tends to pool there. With blood vessels flooded toxins may build up. Dark circles and swelling appear thanks to liquid accumulation under the skin.

Succinic acid accelerates the reparation and growth of new vessels, and redermalization is a solution for the mechanical activation of regenerative skin functions, intensification, and restoration of microcirculation.

Succinic acid blocks the tyrosinase enzyme

Dermal hyperpigmentation is one of the possible causes of periorbital dark circles. Succinic acid is able to block mechanically tyrosinase enzyme that triggers melanin production.

Succinic acid to deal with special periorbital zone anatomy

Due to the special anatomy of the periorbital zone, the dark circles can be more visible to some patients. The main indications are lack of volume and expression of tear-through, shadows caused by pseudo-herniated orbital fat, and thin skin.

Succinic acid is helpful for dermal recovery, increase skin thickness, intensification, and restoration of microcirculation.

Skin biopsy before treatment (A), after a course of injections of a hyaluronic acid only (B), and after a course of injections of XELA REDERM (combination of succinic acid and hyaluronic acid) (C). Stained with hematoxylin-eosin. UV-200

Recommended products for eye zone redermalization

XELA REDERM 1.1 contains 1.1 % hyaluronic acid and 1.6 % succinic acid. This combination is perfectly suitable for periorbital zone corrections.

Redermalization injection techniques

Choose injection technique individually depending on indications and specific skin conditions.

What is succinic acid?

Succinic acid has been found an important component that has provided a breakthrough in improving skin.

Succinic acidic (succinate) is a natural component found in all cells in the body. It contributes to the normalization of microcirculation and activation of lymphatic drainage. It regulates cellular energy exchange and has antioxidant properties. It is also known as able to prevent damage to the cell membrane. Finally, it contributes to the stimulation of the synthesis of basic structural proteins.

High molecular weight hyaluronic acid and succinic acid in XELA REDERM formulations are two active ingredients whose synergetic action gives better results than the mono-product of hyaluronic acid.

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